Tinnitus in COVID-19 Era – A Study on its Association with SARS-CoV-2 and its Outcome

Main Article Content

Paroma Mukherjee
Misbahul Haque
Prasanta Kumar Gure
Sarvesh Premanand Azgaonkar

Abstract

Introduction


Coronavirus disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) virus mainly affecting the respiratory and circulatory system. In many, neuro-otological changes have been noted – tinnitus being one of the leading clinical manifestations which has skipped the limelight due to the other deadly complications of the disease. The study aims to assess the relation between COVID-19 infection and tinnitus, its relation with vaccination against COVID-19 and to assess the change in intensity of tinnitus at the end of 10 weeks after medical treatment in the patients with and without a positive COVID-19 RTPCR (Reverse Transcription-Polymerase Chain Reaction) report.


Materials and Methods


An institution based prospective comparative study was done in a tertiary hospital in Kolkata, West Bengal between July 2021 to December 2021. All patients aged between 18 and 65 years, with recent onset of subjective tinnitus since March 2020 (COVID-19 1st wave), were included in this study. Intensity of tinnitus was assessed at the end of 10 weeks after medical treatment with the help of Tinnitus Handicap Inventory (THI).


Results


            Among the 84 patients with tinnitus - 20 had a history of (H/O) COVID-19 infection, 64 didn’t. Among the 20 patients who developed tinnitus post-COVID-19 infection, 2(10%) had been vaccinated while 39 out of the 64(60.9%) patients without a had been vaccinated against COVID-19 disease. At the end of 10 weeks post-treatment, 6 out of 20(30%) patients with a H/O COVID-19 showed an improvement in THI score– of them, 2 were vaccinated while 33 out of 64(51.56%) patients without a H/O COVID-19 showed improvement in THI score – of them 28 were vaccinated against COVID-19.


Conclusion


Our study concludes that the chances of developing tinnitus is more in those who have not been vaccinated against COVID-19 and post-medication improvement of tinnitus in COVID-19 infected patients was much less than those without a history of COVID-19 infection.

Article Details

How to Cite
1.
Mukherjee P, Haque M, Gure PK, Azgaonkar SP. Tinnitus in COVID-19 Era – A Study on its Association with SARS-CoV-2 and its Outcome. BJOHNS [Internet]. 2023Mar.31 [cited 2024May20];30(2):170-7. Available from: https://www.bjohns.in/journal3/index.php/bjohns/article/view/753
Section
Main article
Author Biographies

Paroma Mukherjee, Medical College Kolkata. 88, College St, College Square, Kolkata, West Bengal 700073

Junior Resident,

Department of Otolaryngology and Head Neck Surgery,

 Medical College & hospital, Kolkata

 

 

Misbahul Haque, Medical College Kolkata. 88, College St, College Square, Kolkata, West Bengal 700073

 

Senior Resident

Department of otolaryngology and head neck surgery

Medical College & hospital, Kolkata

 

Prasanta Kumar Gure, Medical College Kolkata. 88, College St, College Square, Kolkata, West Bengal 700073

Associate professor,

Department of Otolaryngology and Head Neck Surgery, Medical College & hospital, Kolkata, West bengal, India

gureprasanta@gmail.com

9831080522

Sarvesh Premanand Azgaonkar, Goverment Medical College, Near Civil Hospital, A/p.Oras , Tal. Kudal Dist.Sindhudurg (M.S.) INDIAsindhudurg, maharashtra

Assistant Professor,

Department of Otolaryngology and Head Neck Surgery,

Goverment Medical College, Sindhudurg, Maharashtra

References

Hazell J. Incidence, Classification and Models of Tinnitus. Diseases of the Ear. 6th Ed. First Indian Edition. 2006; Isbn 81-8061-933-8

Beukes EW, Baguley DM, Jacquemin L, Lourenco MPCG, et al. Changes in Tinnitus Experiences During the COVID-19 Pandemic. Front Public Health. 2020; 8:592878. doi: 10.3389/fpubh.2020.592878

Singh C, Kawatra R, Gupta J, Awasthi V, Dungana H. Therapeutic Role of Vitamin B12 In Patients of Chronic Tinnitus: A Pilot Study. Noise Health 2016;18(81):93-7

Shemesh Z, Attias J, Ornan M, Shapira N, Shahar A. Vitamin B12 deficiency in patients with chronic tinnitus and noise-induced hearing loss. Am J Otolaryngol. 1993; 14(2): 94-9. doi: 10.1016/0196-0709(93)90046-a

Bauer CA, Brozoski TJ. Effect of gabapentin on the sensation and impact of tinnitus. Laryngoscope 2006; 116(5):675-81. doi: 10.1097/01.MLG.0000216812.65206.CD

McCombe A, Baguley D, Coles R, McKenna L, McKinney C, et al; British Association of Otolaryngologists, Head and Neck Surgeons. Guidelines for the grading of tinnitus severity: the results of a working group commissioned by the British Association of Otolaryngologists, Head and Neck Surgeons, 1999. Clin Otolaryngol Allied Sci. 2001; 26(5):388-93. doi: 10.1046/j.1365-2273.2001.00490.x

Jafari Z, Kolb BE, Mohajerani MH. Hearing Loss, Tinnitus, and Dizziness in COVID-19: A Systematic Review and Meta-Analysis. Can J Neurol Sci. 2022 ;49(2):184-95. doi: 10.1017/cjn.2021.63

Chirakkal P, Al Hail AN, Zada N, Vijayakumar DS. COVID-19 and Tinnitus. Ear Nose Throat J. 2021; 100(2_suppl):160S-162S. doi: 10.1177/0145561320974849

Almufarrij I, Munro KJ. One year on: an updated systematic review of SARS-CoV-2, COVID-19 and audio-vestibular symptoms. Int J Audiol. 2021; 60(12):35-945. doi: 10.1080/14992027.2021.1896793

Liang Y, Xu J, Chu M, Mai J, et al. Neurosensory dysfunction: A diagnostic marker of early COVID-19. Int J Infect Dis. 2020; 98:347-52. doi: 10.1016/j.ijid.2020.06.086

Özçelik Korkmaz M, Eğilmez OK, Özçelik MA, Güven M. Otolaryngological manifestations of hospitalised patients with confirmed COVID-19 infection. Eur Arch Otorhinolaryngol. 2021; 278(5):1675-85. doi: 10.1007/s00405-020-06396-8

Davis HE, Assaf GS, McCorkell L, Wei H. et al. Characterizing long COVID in an international cohort: 7 months of symptoms and their impact. E Clinical Medicine 2021; 38:101019. doi: 10.1016/j.eclinm.2021.101019

Viola P, Ralli M, Pisani D, Malanga D, et al. Tinnitus and equilibrium disorders in COVID-19 patients: preliminary results. Eur Arch Otorhinolaryngol. 2021; 278(10):3725-30. doi: 10.1007/s00405-020-06440-7.

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